Scientists are rethinking the origins of syphilis after discovering a 5,500-year-old fossil in Colombia that suggests the disease may have been around for thousands of years longer than previously thought.
The discovery was made by an anthropologist at Southern Methodist University and her colleagues who found the genome of Treponema pallidum, the bacteria that causes syphilis, in an individual excavated from a rock shelter in the Sabana de Bogotá, Colombia. The team's findings suggest that the disease may have evolved its sexual transmission at least 13,700 years ago.
The origins of syphilis have been debated among scientists for centuries, with many believing it originated in Europe during the Middle Ages. However, the new discovery challenges this idea and suggests that the disease may have had a more ancient origin.
According to researchers, the finding was a lucky break as they were not specifically searching for the genome of Treponema pallidum when they stumbled upon it while studying the DNA of an individual from 5,500 years ago.
The team's lead author, Davide Bozzi, said that the discovery indicates the ancient pan-human distribution of Treponema pallidum subspecies and suggests that various strains were likely traveling with early humans migrating out of Africa.
However, more research is needed to fully understand the origins of syphilis and how it evolved over time. The team hopes to analyze other ancient pathogen genomes from different parts of the world to gain more insights into the history of the disease.
In a way, this discovery reverses our current understanding of the origins of syphilis. While we have been blaming European countries for introducing the disease to Europe, it seems that the bacteria were likely present in humans long before the arrival of European colonizers.
The finding highlights the complexity and diversity of human-pathogen interactions throughout history. The fact that Treponema pallidum was already diverse 5,500 years ago suggests that the relationship between humans and pathogens is much older than we thought.
It also raises questions about how syphilis evolved its sexual transmission and whether it was a single event or a gradual process. Further research will be needed to answer these questions.
For now, scientists are reevaluating their understanding of human history and the role of pathogens in shaping our world.
The discovery was made by an anthropologist at Southern Methodist University and her colleagues who found the genome of Treponema pallidum, the bacteria that causes syphilis, in an individual excavated from a rock shelter in the Sabana de Bogotá, Colombia. The team's findings suggest that the disease may have evolved its sexual transmission at least 13,700 years ago.
The origins of syphilis have been debated among scientists for centuries, with many believing it originated in Europe during the Middle Ages. However, the new discovery challenges this idea and suggests that the disease may have had a more ancient origin.
According to researchers, the finding was a lucky break as they were not specifically searching for the genome of Treponema pallidum when they stumbled upon it while studying the DNA of an individual from 5,500 years ago.
The team's lead author, Davide Bozzi, said that the discovery indicates the ancient pan-human distribution of Treponema pallidum subspecies and suggests that various strains were likely traveling with early humans migrating out of Africa.
However, more research is needed to fully understand the origins of syphilis and how it evolved over time. The team hopes to analyze other ancient pathogen genomes from different parts of the world to gain more insights into the history of the disease.
In a way, this discovery reverses our current understanding of the origins of syphilis. While we have been blaming European countries for introducing the disease to Europe, it seems that the bacteria were likely present in humans long before the arrival of European colonizers.
The finding highlights the complexity and diversity of human-pathogen interactions throughout history. The fact that Treponema pallidum was already diverse 5,500 years ago suggests that the relationship between humans and pathogens is much older than we thought.
It also raises questions about how syphilis evolved its sexual transmission and whether it was a single event or a gradual process. Further research will be needed to answer these questions.
For now, scientists are reevaluating their understanding of human history and the role of pathogens in shaping our world.