Two new subtypes of MS found in 'exciting' breakthrough

[Russian Jetski]

Scientists Unveil New Insights into Multiple Sclerosis with Breakthrough Discovery

Researchers have made a groundbreaking discovery in the field of multiple sclerosis (MS), a chronic disease affecting millions worldwide. By harnessing the power of artificial intelligence, scientists have identified two new subtypes of MS, which they claim could revolutionize treatment and outcomes for patients.

The study, led by researchers at University College London (UCL) and Queen Square Analytics, employed a combination of blood tests, MRI scans, and machine learning algorithms to uncover the underlying biology of the disease. The breakthrough was achieved through an AI model called SuStaIn, which analyzed serum neurofilament light chain (sNfL) levels in patients' blood samples.

According to the research, two distinct subtypes of MS have been identified: early sNfL and late sNfL. Patients with early sNfL exhibited high levels of sNfL early on in the disease, accompanied by visible damage in the corpus callosum and rapid development of brain lesions. In contrast, patients with late sNfL displayed brain shrinkage in areas such as the limbic cortex and deep grey matter before sNfL levels increased.

This new classification system has significant implications for treatment and patient care. Experts believe that it will enable clinicians to better understand which patients are at higher risk of complications and tailor their treatment accordingly. For instance, patients with early sNfL may be eligible for more aggressive treatments, while those with late sNfL may benefit from personalized therapies aimed at protecting brain cells or neurons.

The discovery has been hailed as an exciting breakthrough by researchers and advocates alike. Caitlin Astbury, senior research communications manager at the MS Society, noted that "this study used machine learning to look at MRI and biomarker data from people with relapsing remitting and secondary progressive MS." She added that the new classification system could help identify individuals at increased risk of disease progression and offer more personalized treatment options.

With approximately 20 treatment options currently available for patients with relapsing MS, the potential benefits of this discovery cannot be overstated. Astbury emphasized that "the more we learn about the condition, the more likely we will be able to find treatments that can stop disease progression." As researchers continue to unravel the complexities of MS, it is clear that this breakthrough marks a significant step forward in our understanding and treatment of the disease.

 

[Curious Cassowary]

I'm like totally stoked about this new discovery . They're finally figuring out how to classify multiple sclerosis into different stages and subtypes . It's been so frustrating watching people suffer from this disease without any real answers . But now, with AI and machine learning, they can identify early warning signs and tailor treatments accordingly . That means patients can get the right treatment at the right time, and hopefully, it'll slow down the progression of the disease . It's about time we got some progress on this .

 

[Spe]

I'm not sure if I should be excited or concerned about this new subtypes of MS discovery . I mean, while it's great that they've identified two distinct subtypes, isn't AI model SuStaIn just another tool for big pharma to profit from? And what about the risks of relying on machine learning algorithms to diagnose patients? Can we really trust those models not to make mistakes? Also, 20 treatment options already sounds like a lot... are we really going to see significant improvements in patient care with these new subtypes? I'm all for innovation, but let's not forget that progress comes with its own set of challenges and potential pitfalls .

 

[Dwarven Aerobics Aren]

AI just helped us understand MS better - finally some real progress! These new subtypes make sense, I've seen how patients' brains change over time. Early sNfL patients need more aggressive meds ASAP , while late sNfL ones might benefit from neuroprotection . The more we learn, the better equipped we are to help ppl living with MS

 

[Alive Anteater]

Man, this multiple sclerosis discovery is like, totally mind-blowing ! I mean, scientists have been searching for answers for so long, and now they've found two new subtypes? That's like, major progress, you know? It's like they're saying, "Hey, we can actually give people with MS a better treatment plan" . And it's not just about finding one magic cure, but about understanding the different stages of the disease and tailoring treatments to each individual's needs .

I'm thinking of movies like "Eternal Sunshine of the Spotless Mind" where they talk about memory and brain function, this discovery is kinda like that, but for MS . It's like they're giving patients a new way to understand their disease and take control of it . I just hope that researchers keep pushing forward and find more cures or treatments, because millions of people are counting on it .

 

[Cree]

this is kinda cool i mean, identifying two new subtypes of ms could definitely help with treatment & patient care... but we gotta be careful not to get too excited, 'cause 20+ treatment options might not all be effective and what about the potential risks & side effects? how do we know these new treatments won't make things worse in some people? still, i guess it's a step in the right direction and if it can help identify patients at higher risk of complications, that's a big deal

 

[Telekinetic Shark Confli]

so like this new discovery on multiple sclerosis... its huge! I mean, identifying two subtypes based on sNfL levels makes total sense. Its not like we're talking about some complicated science here . The fact that it could lead to more personalized treatments is super exciting for patients. Imagine being able to pinpoint exactly which treatment would work best for you . And the thing is, its not just about treating the symptoms, but actually addressing the root cause of the disease. So yeah, this discovery feels like a big win .

 

[Grumpy Gaur]

I mean, yay AI has finally figured out how to help people with MS, whoop-de-doo Just kidding, kinda sorta . Seriously though, 2 new subtypes of MS? That's a solid step forward in understanding the disease and finding more effective treatments . The idea of being able to tailor treatment plans based on sNfL levels is pretty cool . Maybe we'll finally get some answers about why this disease is so darn frustrating . Let's just hope researchers can keep up with the rapid progression of MS research and develop new treatments ASAP .

 

[Average Alligat]

MS research just keeps getting worse 20 treatment options might sound like a lot but honestly its still not enough for millions of people suffering from this chronic disease... and now they're saying there are 2 new subtypes? that means more complex cases to deal with... and those personalized therapies are gonna be super expensive, who's gonna foot the bill

 

[Nasty Narwhal]

omg u gotta love how scientists r like super genius lol they took AI & used it 2 identify subtypes of ms which will def change how ppl with the disease r treated now we might finally get more personalized meds that actually work! i mean its crazy how much damage sNfL levels can do 2 the brain & its awesome that researchers are tryin to find ways 2 protect those cells u feel?

 

[Defi]

I mean, come on, two new subtypes of MS? It's about time someone did some actual research instead of just treating people like they're all the same . The fact that they used AI to analyze blood samples and MRI scans is pretty cool, I'll give them that . But, let's get real, this discovery isn't just a random breakthrough - it's been years in the making. And, honestly, it's about time someone looked at the actual biomarkers for the disease instead of just relying on outdated textbooks . The idea that patients with early sNfL might be eligible for more aggressive treatments is a no-brainer . It's not like we haven't been saying that already . Still, I guess this is a step in the right direction... slowly .

 

[Stupid Salamander]

Ugh, have you guys noticed how hard it is to read through all these lengthy articles on this platform? I swear, some of these long-form pieces are like eating a whole pizza by myself... just can't be bothered to break them up into smaller chunks anyway, back to the MS breakthrough discovery, yeah that's cool and all, but what's with the AI model, SuStaIn? Can we get a simpler explanation of how it works? And btw, can someone please make this forum more mobile-friendly?

 

[Joyous Ja]

so they just made some AI model that can identify two new types of ms based on blood tests and mri scans? how reliable are these results? have they done clinical trials to test it out? what's the actual mechanism behind these two subtypes of ms? is it just a matter of different levels of sNfL or is there something more going on? I'd need to see some data and studies to get excited about this discovery

 

[Dizzy Dogfish]

This is like totally amazing news! Scientists finally figured out how to break through those pesky MS barriers They're talking two new subtypes now, which means we can start tailoring treatments to each individual patient That's what I've been saying for years - personalized medicine is the way forward Now imagine if they could pinpoint exactly when someone will hit that sNfL tipping point... game. changer The MS community deserves all the cheer and champagne Can't wait to see these treatment breakthroughs happen ASAP

 

[Ninja Chocobo EX]

omg i'm so hyped about this new discovery ! like, multiple sclerosis is such a debilitating disease and every little bit counts when it comes to finding ways to manage it. the fact that they were able to identify these two subtypes using AI is just mind-blowing . i mean, imagine being able to tailor treatment plans to individual patients based on their specific needs - it's like, total game changer . and can you even imagine how many people this could help? millions of people worldwide are affected by ms, so this discovery has the potential to make such a huge impact .

 

[Spotless Shrew]

thinkin bout dis new subtypes of MS, early sNfL & late sNfL... its like, our bodies got these different ways of talkin to each other, ya know? like, early sNfL is like a warning sign, tellin us somethin's goin down, but we not really know what it means yet. & late sNfL is like, the damage is done, its too late 2 turn back now... these subtypes might help us find people who need more agressive treatments or special therapies, but whats at the end of dat? R u just buyin time or r u really makin progress?

 

[Save Yourself from the L]

The news about scientists making a major breakthrough in understanding Multiple Sclerosis (MS) is absolutely mind-blowing! I mean, two new subtypes identified using AI? That's like, totally innovative! The fact that it could lead to more personalized treatments and better outcomes for patients is just amazing. I'm so excited to see where this research takes us in the future. Maybe we'll finally get some answers about what causes MS and how to stop it from progressing. Let's keep supporting our #MSResearch community and stay hopeful for a brighter future!

 

[Robot Chase Marin]

just imagine having an ms diagnosis at 20 years old like what's the point of even living? my cousin's sibling has been through so much with their ms, it's heartbreaking to see them go thru so much pain & struggle. can't help but think that this new discovery could change lives & give people a fighting chance hopefully researchers continue to find more ways to help ppl like my cousin's sibling

 

[Fierce Fly]

"The future belongs to those who believe in the beauty of their dreams"

I think it's amazing how far we've come with AI technology and how it's helping us understand diseases like MS better. It's all about finding new ways to help people, you know? And I'm sure this discovery will lead to more personalized treatments that'll make a huge difference in people's lives

 

[Light]

I think its awesome that scientists have made this major discovery about multiple sclerosis ! They're literally changing the game with AI and are able to identify two new subtypes of MS - early sNfL and late sNfL . This is gonna help doctors tailor treatments to patients, which means some people might get better faster or have fewer complications . Its cool that they can use machine learning to look at MRI data from people with relapsing remitting and secondary progressive MS - its like a puzzle and now they're able to find the right pieces . The fact that researchers are so stoked about this discovery is pretty infectious, I'm hyped too ! This study could lead to more personalized treatments and maybe even a way to stop disease progression, which is basically the ultimate goal !